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Waldenstrm's macroglobulinemia in young African-American adults by Ahmed, Shabbir; Shurafa, Muhammad S.; Bishop, Carter R.; Varterasian, Mary is a Medicine article available to read on EtoBox.
What is Waldenstrm's macroglobulinemia in young African-American adults about?
We have identified five African-American patients with Waldenstro ̈m's macroglobulinemia (WM) diagnosed at a young age (ages 35, 38, 38, 40, 51; 4 males, 1 female). All had a history of intravenous heroin abuse and four also used cocaine. Their manner of presentation and clinical course were typical. Three of three patients tested for the hepatitis C virus (HCV) were positive and three of three patients tested were HIV negative. The potential relationship between intravenous drug abuse and/or HCV to development of WM in this group of young patients is provocative, especially since a polyclonal increase in serum IgM is commonly seen in chronic intravenous heroin addicts. More recently, the contribution of HCV is being evaluated in lymphoproliferative disorders. Although WM is typically a disease of older people, it should also be considered in the differential in a young patient with a suggestive clinical picture. Am.
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- Author
- Ahmed, Shabbir; Shurafa, Muhammad S.; Bishop, Carter R.; Varterasian, Mary
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0361-8609)
- Published
- 1999
- Language
- EN
- Field
- Medicine (Health Sciences)