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Can I read 1,1,1,3,3,3-Hexafluoroisopropanol: A Recyclable Organocatalyst for N -Boc Protection of Amines on EtoBox?
1,1,1,3,3,3-Hexafluoroisopropanol: A Recyclable Organocatalyst for N -Boc Protection of Amines by Akbar Heydari; Samad Khaksar; Mahmood Tajbakhsh is a Chemistry article available to read on EtoBox.
What is 1,1,1,3,3,3-Hexafluoroisopropanol: A Recyclable Organocatalyst for N -Boc Protection of Amines about?
A simple and efficient protocol for the chemoselective mono-N-Boc protection of various structurally diverse amines with di-tert-butyl dicarbonate using 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) as solvent and catalyst is described. The catalyst can be readily separated from the reaction products and recovered for direct reuse. No competitive side reactions such as formation of isocyanate, urea, and N,N-di-Boc were observed. a-Amino alcohols afforded the N-Boc derivatives without oxazolidinone formation.
Who reads 1,1,1,3,3,3-Hexafluoroisopropanol: A Recyclable Organocatalyst for N -Boc Protection of Amines?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Akbar Heydari; Samad Khaksar; Mahmood Tajbakhsh
- Publisher
- Thieme Medical Publishers; Georg Thieme Verlag KG; Georg Thieme Verlag (ISSN 0039-7881)
- Published
- 2008
- Language
- EN
- Field
- Chemistry (Physical Sciences)
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