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Can I read Optimisation of Radiation Therapy in Bladder Preservation Therapy for Patients With Clinical Stage T2N0M0 Bladder Cancer on EtoBox?
Optimisation of Radiation Therapy in Bladder Preservation Therapy for Patients With Clinical Stage T2N0M0 Bladder Cancer by M. Nakata; T. Shimbo; A. Kihara; C. Sato; A. Hori; H. Yoshioka; K. Yoshida; K. Nihei is a Agricultural and Biological Sciences article available to read on EtoBox.
What is Optimisation of Radiation Therapy in Bladder Preservation Therapy for Patients With Clinical Stage T2N0M0 Bladder Cancer about?
## Aims: A novel bladder preservation therapy, the omc (osaka medical college) regimen, which combines radiation therapy with balloon-occluded arterial infusion of anticancer agents, is a treatment option for patients with muscle-invasive bladder cancer (mibc). we retrospectively analysed the effects of changes in radiation dose and irradiation field on treatment efficacy and adverse events.the purpose of this study is to use the results of this study to help determine a course of radiation therapy for bladder preservation therapy of ct2n0m0 mibc. ## Materials and methods: We examined 352 patients with clinical stage t2n0m0 (ct2n0m0) mibc classified into the following groups based on the irradiation method: group a, the whole pelvis (50 gy/25 fractions) + local bladder (10 gy/5 fractions); group b, the small pelvis (50 gy/25 fractions) + local bladder (10 gy/5 fractions); group c, the whole pelvis (40 gy/20 fractions) + local bladder (10 gy/5 fractions). ## Results: The complete response rate, 3-year overall survival and progression-free survival rates in group a were 92.9%, 94.9% and 82.1%, respectively; in group b were 87.2%, 86.7% and 76.7%, respectively; and in group c were 95.
Who reads Optimisation of Radiation Therapy in Bladder Preservation Therapy for Patients With Clinical Stage T2N0M0 Bladder Cancer?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- M. Nakata; T. Shimbo; A. Kihara; C. Sato; A. Hori; H. Yoshioka; K. Yoshida; K. Nihei
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)