Opening book details…
Can I read Recent Progress of Micro/nanomotors to Overcome Physiological Barriers in the Gastrointestinal Tract on EtoBox?
Recent Progress of Micro/nanomotors to Overcome Physiological Barriers in the Gastrointestinal Tract by Shuhao Zhang; Chaoran Zhu; Wanting Huang; Hua Liu; Mingzhu Yang; Xuejiao Zeng; Zhenzhong Zhang; Junjie Liu; Jinjin Shi; Yurong Hu; Xiufang Shi; Zhi-Hao Wang is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Recent Progress of Micro/nanomotors to Overcome Physiological Barriers in the Gastrointestinal Tract about?
Oral administration is a convenient administration route for gastrointestinal disease therapy with good patient compliance. But the nonspecific distribution of the oral drugs may cause serious side effects. In recent years, oral drug delivery systems (ODDS) have been applied to deliver the drugs to the gastrointestinal disease sites with decreased side effects. However, the delivery efficiency of ODDS is tremendously limited by physiological barriers in the gastrointestinal sites, such as the long and complex gastrointestinal tract, mucus layer, and epithelial barrier. Micro/nanomotors (MNMs) are micro/nanoscale devices that transfer various energy sources into autonomous motion. The outstanding motion characteristics of MNMs inspired the development of targeted drug delivery, especially the oral drug delivery. However, a comprehensive review of oral MNMs for the gastrointestinal diseases therapy is still lacking. Herein, the physiological barriers of ODDS were comprehensively reviewed. Afterward, the applications of MNMs in ODDS for overcoming the physiological barriers in the past 5 years were highlighted. Finally, future perspectives and challenges of MNMs in ODDS are discussed
Who reads Recent Progress of Micro/nanomotors to Overcome Physiological Barriers in the Gastrointestinal Tract?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Shuhao Zhang; Chaoran Zhu; Wanting Huang; Hua Liu; Mingzhu Yang; Xuejiao Zeng; Zhenzhong Zhang; Junjie Liu; Jinjin Shi; Yurong Hu; Xiufang Shi; Zhi-Hao Wang
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)