About this document
LC-MS Method for Dolutegravir in Breast Milk by Yi Wang is a document available to read on EtoBox.
This document details the validation and clinical application of a novel LC-MS method for quantifying dolutegravir in breast milk, aimed at assessing pharmacokinetics in breastfeeding mothers and their infants. The method demonstrated robustness, accuracy, and precision, adhering to FDA and EMA guidelines, and is suitable for use in low-resource settings. The study highlights the importance of understanding ARV transfer through breast milk to mitigate risks of infant exposure and drug resistance.
- Author
- Yi Wang
- Language
- EN