Can I read Increased Levels of Total Oxidant Status and Decreased Activity of Arylesterase in Migraineurs on EtoBox?

Increased Levels of Total Oxidant Status and Decreased Activity of Arylesterase in Migraineurs by Necat Yilmaz; Ozgur Aydin; Aysenur Yegin; Aysun Tiltak; Esin Eren is a Medicine article available to read on EtoBox.

What is Increased Levels of Total Oxidant Status and Decreased Activity of Arylesterase in Migraineurs about?

## Objectives: There is strong evidence associating migraine with a variety of comorbid disorders, including cardiovascular disease and stroke, in which oxidative stress seems to be an important underlying mechanism. the aim of the study was to investigate in migraineurs the body oxidant/antioxidant balance and paraoxonase enzyme activities as a measure of hdl functionality. ## Design and methods: Oxidative stress index, total oxidant status and antioxidant status were examined in addition to the paraoxonase and arylesterase enzyme activities in sixty-two migraineurs and fifty healthy control subjects. ## Results: Serum arylesterase activities were significantly lower in migraineurs (p=0.0065), whereas total oxidant status was higher in patients compared to the controls (p=0.0035). ## Conclusions: This preliminary study showed that oxidative/antioxidative balance shifted towards the oxidative status in migraine. moreover, the results also suggested that decreased arylesterase activities might be associated with hdl-related disfunction.

Who reads Increased Levels of Total Oxidant Status and Decreased Activity of Arylesterase in Migraineurs?

Author

Necat Yilmaz; Ozgur Aydin; Aysenur Yegin; Aysun Tiltak; Esin Eren

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0009-9120)

Published

2011

Language

EN

Field

Medicine (Health Sciences)