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The Place for Starches and Other Colloids by Ripenmeet Salhotra; Adrian Wong; Manu L. N. G. Malbrain is a book available to read on EtoBox.

What is The Place for Starches and Other Colloids about?

## Abstract This chapter provides a comprehensive review of synthetic colloids, specifically hydroxyethyl starch (HES) solutions, and their role in resuscitation of critically ill, perioperative, and trauma patients. This chapter addresses various questions, including the crystalloid versus colloid debate, the strengths and weaknesses of different fluid trials and meta-analyses, and the specific situations or patient groups where colloids may have an advantage. This chapter focuses on the results of five major trials that compare the use of crystalloids versus colloids in critically ill patients. The 6S study and the CHEST trial confirmed the suspicion of renal damage associated with HES solutions, and the European Medicines Agency’s (EMA) safety committee prohibited the use of HES solutions in critically ill, septic, and burn patients, or those with kidney injury in 2013. However, many questions and controversies remained thereafter and more recently the European Commission has suspended the marketing authorizations of HES solutions for infusion. The use of HES and other synthetic colloids should be restricted to resuscitation in the perioperative setting or in limited volumes wit

Author

Ripenmeet Salhotra; Adrian Wong; Manu L. N. G. Malbrain

Publisher

Springer International Publishing AG

Published

2023

Language

EN

ISBN

9783031422058

Subjects

Medical, Medicine