Opening book details…
Can I read Prognostic significance of microscopic size in peripherally located scar-associated clinical stage I lung carcinomas on EtoBox?
Prognostic significance of microscopic size in peripherally located scar-associated clinical stage I lung carcinomas by Trejo Bittar, Humberto E.; Jerome, Jacob A.; Hartman, Douglas; Pantanowitz, Liron; Mehrad, Mitra; Dacic, Sanja is a Medicine article available to read on EtoBox.
What is Prognostic significance of microscopic size in peripherally located scar-associated clinical stage I lung carcinomas about?
## Objectives: Staging of non-small cell lung carcinoma associated with scar is not discussed in detail in the current american joint committee on cancer staging manual. the recommendation is to include the scar area in the tumor size measurement unless the tumor represents a small focus at the edge of the scar. the aim of this study is to investigate if subtraction of the size of the central scar from the total gross size of surgically resected peripheral clinical stage i non-small cell lung carcinoma improves patient stratification into more accurate prognostic groups. ## Materials and methods: Hematoxylin and eosin sections of 148 non-small cell lung carcinomas (98 adenocarcinomas and 50 squamous cell carcinomas) were reviewed, including 44 adenocarcinomas and 9 squamous cell carcinomas with scar and 54 adenocarcinomas and 41 squamous cell carcinomas without scar. the microscopic size of the invasive tumor component was determined after the average percentage of scar tissue was subtracted from the grossly measured tumor diameter. manual results were compared to digital image analysis. ## Results: Adenocarcinoma with scar were associated with better overall (80.5 % vs. 63.2 %, p
Who reads Prognostic significance of microscopic size in peripherally located scar-associated clinical stage I lung carcinomas?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Trejo Bittar, Humberto E.; Jerome, Jacob A.; Hartman, Douglas; Pantanowitz, Liron; Mehrad, Mitra; Dacic, Sanja
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0169-5002)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)