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Monitoring of Renal Function in Patients with Spinal Cord Injury by S.A. Macdiarmid; W.J. McIntyre; A. Anthony; R.R. Bailey; J.G. Turner; E.P. Arnold is a Medicine article available to read on EtoBox.

What is Monitoring of Renal Function in Patients with Spinal Cord Injury about?

**Objective** To assess the sensitivity of serum creatinine level in detecting clinically important and early deterioration of renal function in patients with spinal cord injury (SCI), and to evaluate the optimal method of determining creatinine clearance in these patients. **Patients and methods** The serum creatinine level of 36 patients (25 paraplegics and 11 quadriplegics) was evaluated and compared with the corresponding measured creatinine clearance rate. Correlations were also assessed between the creatinine clearance measured by 24‐h endogenous clearance, single‐shot ^99m^Tc‐labelled diethylenetriamine pentaacetic acid (^99m^Tc‐DTPA) clearance technique, and the Cockcroft–Gault formula, to test their validity. **Results** Of the 36 patients 11 (31%) had a measured creatinine clearance of < 100 mL/min (mean 84.8) and a corresponding normal serum creatinine level. Creatinine clearance calculated by the Cockcroft–Gault formula did not correlate well with that measured by the 24‐h endogenous clearance (__r__ = 0.426) and ^99m^Tc‐DTPA clearance (__r__ = 0.366), overestimating creatinine clearance in all but three patients. The mean (sd) difference between the creatinine clearanc

Who reads Monitoring of Renal Function in Patients with Spinal Cord Injury?

Author

S.A. Macdiarmid; W.J. McIntyre; A. Anthony; R.R. Bailey; J.G. Turner; E.P. Arnold

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1464-4096)

Published

2000

Language

EN

Field

Medicine (Health Sciences)