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Lumbar Spine Fusion Outcomes Using a Cellular Bone Allograft with Lineage-committed Bone-forming Cells in 96 Patients by Hossein Elgafy; Bradley Wetzell; Marshall Gillette; Hassan Semaan; Andrea Rowland; Christopher A. Balboa; Thomas A. Mierzwa; Julie B. McLean; Kimberly Dorsch; Mark A. Moore is a Medicine article available to read on EtoBox.

What is Lumbar Spine Fusion Outcomes Using a Cellular Bone Allograft with Lineage-committed Bone-forming Cells in 96 Patients about?

## Abstract ## Background Instrumented posterior lumbar fusion (IPLF) with and without transforaminal interbody fusion (TLIF) is a common treatment for low back pain when conservative interventions have failed. Certain patient comorbidities and lifestyle risk factors, such as obesity and smoking, are known to negatively affect these procedures. An advanced cellular bone allograft (CBA) with viable osteogenic cells (V-CBA) has demonstrated high fusion rates, but the rates for patients with severe and/or multiple comorbidities remain understudied. The purpose of this study was to assess fusion outcomes in patients undergoing IPLF/TLIF using V-CBA with baseline comorbidities and lifestyle risk factors known to negatively affect bone fusion. ## Methods This was a retrospective study of de-identified data from consecutive patients at an academic medical center who underwent IPLF procedures with or without TLIF, and with V-CBA. Baseline patient and procedure characteristics were assessed. Radiological outcomes included fusion rates per the Lenke scale. Patient-reported clinical outcomes were evaluated via the Oswestry Disability Index (ODI) and Visual Analog Scale (VAS) for back and leg

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Author

Hossein Elgafy; Bradley Wetzell; Marshall Gillette; Hassan Semaan; Andrea Rowland; Christopher A. Balboa; Thomas A. Mierzwa; Julie B. McLean; Kimberly Dorsch; Mark A. Moore

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)