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Preoperative direct oral anticoagulants treatment and all-cause mortality in elderly patients with hip fracture: A retrospective cohort study by Walid Saliba; Anat Arbel; Zomoroda Abu-Full; Shai Cohen; Gad Rennert; Meir Preis is a Medicine article available to read on EtoBox.

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## Introduction: Hip fracture is common among the elderly and is associated with increased morbidity and mortality, particularly when surgery is delayed. direct oral anticoagulants (doacs) use might increase bleeding and postpone hip repair surgery. we aimed to assess the association between preoperative doacs use and adverse outcomes in elderly patients with hip fracture. ## Materials and methods: This retrospective cohort study included all elderly patients (≥65 years), from the district of haifa and western galilee, israel, who underwent hip repair surgery for hip fracture between 2014 and 2018. regression models with adjustment for propensity score were used to assess the association with all-cause mortality and other adverse outcomes. ## Results: A total of 3418 patients with hip fracture were included of whom 163 (4.8%) were vitamin k antagonists (vkas) users and 247 (7.2%) were docas users. propensity score adjusted models revealed that, compared to no anticoagulants use, doacs use were independently associated with decreased risk of 30-day and 90-day mortality; hr 0.38 (95% ci, 0.17-0.88) and 0.47 (0.27-0.82), respectively. no significant associations were detected between

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Author

Walid Saliba; Anat Arbel; Zomoroda Abu-Full; Shai Cohen; Gad Rennert; Meir Preis

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0049-3848)

Published

2020

Language

EN

Field

Medicine (Health Sciences)