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Gamma Knife Stereotactic Radiosurgery for Salivary Gland Neoplasms with Base of Skull Invasion Following Neutron Radiotherapy by James G. Douglas; Robert Goodkin; George E. Laramore is a scholarly article available to read on EtoBox.

What is Gamma Knife Stereotactic Radiosurgery for Salivary Gland Neoplasms with Base of Skull Invasion Following Neutron Radiotherapy about?

## Abstract ## Background. Our aim was to examine the outcome of patients treated with a planned gamma knife boost after completion of neutron radiotherapy for salivary gland neoplasms involving the base of skull. ## Methods. Thirty‐four patients with salivary gland neoplasms involving the base of skull were treated from 2001 to 2005 at our institution. These results were compared with a similar historical group treated at our institution from 1984 to 2000. The patients had the following characteristics: median age: 54 years (range, 23–80); median follow‐up period: 20.5 months (range, 4–55); women‐to‐men patient ratio: 1.1:1; histology: 29 adenoid cystic, 3 adenocarcinoma, 1 acinic cell, 1 mucoepidermoid; primary sites of disease: 6 nasopharyngeal, 14 paranasal sinuses, 4 parotid gland, 8 oral cavity, 1 lacrimal gland, and 1 auditory canal. All patients had gross residual disease at the time of treatment. The median neutron dose prescribed to isocenter was 19.2 nGy and the median dose to the effected temporal tip was 11.98 nGy. The median prescribed gamma knife dose was 12 Gy to the 50% isodose line. The median number of isocenters was 17. The median target volume treated was 12.4

Author

James G. Douglas; Robert Goodkin; George E. Laramore

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 1043-3074)

Published

2007

Language

EN