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What is Hemoglobin S Mutation and Effects about?

1. The document discusses various abnormal hemoglobins including HbS (sickle cell hemoglobin), HbC, Hb Gun Hill, Hb Constant Spring, and Hb Lepore. It describes the genetic mutations that cause each one and their effects. 2. Sickle cell disease results from a single amino acid substitution that causes hemoglobin S to aggregate and distort red blood cells into a sickle shape, resulting in hemolytic anemia. People with sickle cell trait usually do not have symptoms. 3. Unstable hemoglobins like Hb Gun Hill

Author

kep1313

Language

EN