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Can I read Stimulation of Cell Growth and Inhibition of Prostacyclin Production by Heparin in Human Umbilical Vein Endothelial Cells on EtoBox?
Stimulation of Cell Growth and Inhibition of Prostacyclin Production by Heparin in Human Umbilical Vein Endothelial Cells by N. Hasegawa; M. Yamamoto; K. Yamamoto is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Stimulation of Cell Growth and Inhibition of Prostacyclin Production by Heparin in Human Umbilical Vein Endothelial Cells about?
We characterized human umbilical vein (HUV) endothelial cells as to cell growth and prostacyclin production to get a better understanding of the properties of endothelial cells. Endothelial cell growth supplement (ECGS) and basic fibroblast growth factor (FGF) stimulated HUV endothelial cell growth. Heparin further enhanced the cell growth stimulated by ECGS, but not the cell growth stimulated by FGF or in the absence of these growth factors. In the presence of ECGS, the prostacyclin-producing capacity of the cells was inhibited by heparin. However, in the presence of FGF of in the absence of growth factors, heparin did not inhibit prostacyclin production. Therefore, it is likely that there is a specific correlation between heparin and growth factors for endothelial cells in the blood vessel to maintain nonthrombogenicity properly. Heparin-treated cultures may not be suitable for some examinations of prostacyclin production by vascular endothelial cells.
Who reads Stimulation of Cell Growth and Inhibition of Prostacyclin Production by Heparin in Human Umbilical Vein Endothelial Cells?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- N. Hasegawa; M. Yamamoto; K. Yamamoto
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0021-9541)
- Published
- 1988
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)