About this document
Hepcidin Response in HFE Hemochromatosis by budilubispk is a document available to read on EtoBox.
This case report discusses a p.C282Y homozygous patient with HFE hereditary hemochromatosis who exhibited elevated hepcidin levels during systemic inflammation, despite typically low hepcidin levels associated with the condition. The findings suggest that inflammation can upregulate hepcidin production via the JAK/STAT3 pathway, even when the BMP/SMAD pathway is impaired. This case highlights the complex interplay between iron metabolism and inflammatory responses in patients with hereditary hemochromatosis
- Author
- budilubispk
- Language
- EN