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What is eNOS Polymorphisms and Sickle Cell Crisis about?

This study investigates the association of eNOS gene polymorphisms (−786 T>C and 27 bp VNTR) with vaso-occlusive crises in sickle cell anemia patients in Odisha, India. Results indicate that mutant alleles are significantly more frequent in SCA patients, particularly in those with severe phenotypes, suggesting a link between these polymorphisms and disease severity. The findings highlight that certain genotypes are associated with milder phenotypes and higher hemoglobin levels, while others correlate with s

Author

Pradosh Acharya

Language

EN