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Recommendations for permanent prostate brachytherapy with 131Cs: A consensus report from the Cesium Advisory Group by William S. Bice; Bradley R. Prestidge; Steven M. Kurtzman; Sushil Beriwal; Brian J. Moran; Rakesh R. Patel; Mark J. Rivard is a Medicine article available to read on EtoBox.

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PURPOSE: Published clinical information on the safety and efficacy of 131 Cs implants is limited. We provide consensus recommendations for 131 Cs prostate brachytherapy based on experience to date. ## METHODS AND MATERIALS: The Cesium Advisory Group (CAG) consists of experienced 131 Cs users. Recommendations are based on three clinical trials, one of which has completed accrual and has been published in the peer reviewed literature, and combined CAG experience of more than 1200 131 Cs implants. RESULTS: We recommend using 1.059 cGy h À1 U À1 as the dose rate constant for the IsoRay source. The prescription for monotherapy implants is 115 Gy and when combined with 45e50 Gy external beam it is 85 Gy. Suggested individual source strength ranges from 1.6 to 2.2 U. The release criterion for 131 Cs implants is 6 mR h À1 at 1 m. 131 Cs brachytherapy should be performed differently from 125 I and 103 Pd brachytherapy: source placement is further from the urethra and rectum; the prostate V 150 should be <45%; sufficient margins may be obtained while limiting source placement to the capsule or close to the capsule. The increased dose rate may cause degradation of postimplant quantifiers due

Who reads Recommendations for permanent prostate brachytherapy with 131Cs: A consensus report from the Cesium Advisory Group?

Author

William S. Bice; Bradley R. Prestidge; Steven M. Kurtzman; Sushil Beriwal; Brian J. Moran; Rakesh R. Patel; Mark J. Rivard

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1538-4721)

Published

2008

Language

EN

Field

Medicine (Health Sciences)