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Risk of Esketamine Anesthesia on the Emergence Delirium in Preschool Children After Minor Surgery: a Prospective Observational Clinical Study by Sai Chen; Jin-Jin Yang; Yue Zhang; Lei Lei; Di Qiu; Hui-Min Lv; Zhen-Tao Sun; Kenji Hashimoto; Jian-Jun Yang is a Medicine article available to read on EtoBox.

What is Risk of Esketamine Anesthesia on the Emergence Delirium in Preschool Children After Minor Surgery: a Prospective Observational Clinical Study about?

Emergence delirium (ED) is a common mental complication during recovery from anesthesia. However, studies on the effects of esketamine, an intravenous anesthetic for pediatrics, on ED are still lacking. This study aimed to investigate the effects of a single-dose of esketamine during anesthesia induction on ED after minor surgery in preschool children. A total of 230 children (aged 2-7 years) completed the study. The exposed group (0.46 mg kg -1 : average dose of esketamine) was associated with an increased incidence of ED and a higher maximum Pediatric Anesthesia Emergence Delirium score than the nonexposed group. The length of post-anesthesia care unit stay was longer in the exposed group than the non-exposed group. In contrast, extubation time, face, legs, activity, cry, and consolability (FLACC) scores, and the proportions of rescue analgesics were comparable between the two groups. Furthermore, five factors, including preoperative anxiety scores, sevoflurane and propofol compared with sevoflurane alone for anesthesia maintenance, dezocine for postoperative analgesia, FLACC scores, and esketamine exposure, were associated with ED. In conclusion, a near-anesthetic single-dose of

Who reads Risk of Esketamine Anesthesia on the Emergence Delirium in Preschool Children After Minor Surgery: a Prospective Observational Clinical Study?

Author

Sai Chen; Jin-Jin Yang; Yue Zhang; Lei Lei; Di Qiu; Hui-Min Lv; Zhen-Tao Sun; Kenji Hashimoto; Jian-Jun Yang

Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Medicine (Health Sciences)