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ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis by David W. Brossier; Lyvonne N. Tume; Anais R. Briant; Corinne Jotterand Chaparro; Clémence Moullet; Shancy Rooze; Sascha C. A. T. Verbruggen; Luise V. Marino; Fahad Alsohime; Sophie Beldjilali; Fabrizio Chiusolo; Leonardo Costa; Capucine Didier; Stavroula Ilia; Nyandat L. Joram; Martin C. J. Kneyber; Eva Kühlwein; Jorge Lopez; Jesus López-Herce; Huw F. Mayberry; Fortesa Mehmeti; Magdalena Mierzewska-Schmidt; Maria Miñambres Rodríguez; Claire Morice; John V. Pappachan; Florence Porcheret; Leonor Reis Boto; Luregn J. Schlapbach; Hakan Tekguc; Konstantinos Tziouvas; Jean-Jacques Parienti; Isabelle Goyer; Frederic V. Valla; the Metabolism Endocrinology and Nutrition section of the European Society of Pediatric and Neonatal Intensive Care (ESPNIC) is a Medicine article available to read on EtoBox.

What is ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis about?

## Purpose Intravenous maintenance fluid therapy (IV-MFT) prescribing in acute and critically ill children is very variable among pediatric health care professionals. In order to provide up to date IV-MFT guidelines, the European Society of Pediatric and Neonatal Intensive Care (ESPNIC) undertook a systematic review to answer the following five main questions about IV-MFT: (i) the indications for use (ii) the role of isotonic fluid (iii) the role of balanced solutions (iv) IV fluid composition (calcium, magnesium, potassium, glucose and micronutrients) and v) and the optimal amount of fluid. ## Methods A multidisciplinary expert group within ESPNIC conducted this systematic review using the Scottish Intercollegiate Guidelines Network (SIGN) grading method. Five databases were searched for studies that answered these questions, in acute and critically children (from 37 weeks gestational age to 18 years), published until November 2020. The quality of evidence and risk of bias were assessed, and meta-analyses were undertaken when appropriate. A series of recommendations was derived and voted on by the expert group to achieve consensus through two voting rounds. ## Results 56 papers me

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Author

David W. Brossier; Lyvonne N. Tume; Anais R. Briant; Corinne Jotterand Chaparro; Clémence Moullet; Shancy Rooze; Sascha C. A. T. Verbruggen; Luise V. Marino; Fahad Alsohime; Sophie Beldjilali; Fabrizio Chiusolo; Leonardo Costa; Capucine Didier; Stavroula Ilia; Nyandat L. Joram; Martin C. J. Kneyber; Eva Kühlwein; Jorge Lopez; Jesus López-Herce; Huw F. Mayberry; Fortesa Mehmeti; Magdalena Mierzewska-Schmidt; Maria Miñambres Rodríguez; Claire Morice; John V. Pappachan; Florence Porcheret; Leonor Reis Boto; Luregn J. Schlapbach; Hakan Tekguc; Konstantinos Tziouvas; Jean-Jacques Parienti; Isabelle Goyer; Frederic V. Valla; the Metabolism Endocrinology and Nutrition section of the European Society of Pediatric and Neonatal Intensive Care (ESPNIC)

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)