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Chlorinated Nucleotides and Analogs as Potential Disinfection Byproducts in Drinking Water by Guangrong Sun; Han Yeong Kaw; Meijiao Zhou; Pei Guo; Lizhong Zhu; Wei Wang is a Environmental Science article available to read on EtoBox.

What is Chlorinated Nucleotides and Analogs as Potential Disinfection Byproducts in Drinking Water about?

Identification of emerging disinfection byproducts (DBPs) of health relevance is important to uncover the health risk of drinking water observed in epidemiology studies. In this study, mutagenic chlorinated nucleotides were proposed as potential DBPs in drinking water, and the formation and transformation pathways of these DBPs in chlorination of nucleotides were carefully investigated. A total of eleven chlorinated nucleotides and analogs were provisionally identified as potential DBPs, such as monochloro uridine/cytidine/adenosine acid and dichloro cytidine acid, and the formation mechanisms involved chlorination, decarbonization, hydrolysis, oxidation and decarboxylation. The active sites of nucleotides that reacted with chlorine were on the aromatic heterocyclic rings of nucleobases, and the carbon among the two nitrogen atoms in the nucleobases tended to be transformed into carboxyl group or be eliminated, further forming ring-opening or reorganization products. Approximately 0.2–4.0 % (mol/mol) of these chlorinated nucleotides and analogs finally decomposed to small-molecule aliphatic DBPs, primarily including haloacetic acids, trichloromethane, and trichloroacetaldehyde. Eig

Who reads Chlorinated Nucleotides and Analogs as Potential Disinfection Byproducts in Drinking Water?

Author

Guangrong Sun; Han Yeong Kaw; Meijiao Zhou; Pei Guo; Lizhong Zhu; Wei Wang

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Environmental Science (Physical Sciences)