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Myocardial perfusion during cardiopulmonary resuscitation (CPR): effects of 10, 25 and 50% coronary stenoses by Karl B Kern; Bernardo de la Guardia; Gordon A Ewy is a Medicine article available to read on EtoBox.

What is Myocardial perfusion during cardiopulmonary resuscitation (CPR): effects of 10, 25 and 50% coronary stenoses about?

Myocardial blood flow under normal physiologic conditions remains relatively unaltered by coronary lesions with diameter stenosis of less than 70%. However, during cardiac arrest and cardiopulmonary resuscitation (CPR), autoregulation of coronary blood flow is compromised. We studied the effect of previously considered 'trivial' coronary stenoses of 10, 25 and 50% on distal myocardial perfusion in 39 swine undergoing CPR for cardiac arrest. Endocardial blood flow distal to the stenosis was significantly less than that proximal in all the different stenoses groups (P B0.05). A 50% diameter stenosis also compromised epicardial blood flow distal to the stenosis (P B0.05). This study suggests that any coronary lesion may compromise myocardial perfusion during CPR. Since the vast majority of cardiac arrest victims have coronary artery disease, careful attention to maximizing myocardial blood flow during CPR is needed.

Who reads Myocardial perfusion during cardiopulmonary resuscitation (CPR): effects of 10, 25 and 50% coronary stenoses?

Author

Karl B Kern; Bernardo de la Guardia; Gordon A Ewy

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0300-9572)

Published

1998

Language

EN

Field

Medicine (Health Sciences)