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Can I read Intrinsic Timescales and Predictive Allostatic Interoception in Brain Health and Disease on EtoBox?

Intrinsic Timescales and Predictive Allostatic Interoception in Brain Health and Disease by Agustin Ibanez; Georg Northoff is a Neuroscience article available to read on EtoBox.

What is Intrinsic Timescales and Predictive Allostatic Interoception in Brain Health and Disease about?

The cognitive neuroscience of brain diseases faces challenges in understanding the complex relationship between brain structure and function, the heterogeneity of brain phenotypes, and the lack of dimensional and transnosological explanations. This perspective offers a framework combining the predictive coding theory of allostatic interoceptive overload (PAIO) and the intrinsic neural timescales (INT) theory to provide a more dynamic understanding of brain health in psychiatry and neurology. PAIO integrates allostasis and interoception to assess the interaction between internal patterns and environmental stressors, while INT shows that different brain regions operate on different intrinsic timescales. The allostatic overload can be understood as a failure of INT, which involves a breakdown of proper temporal integration and segregation. This can lead to dimensional disbalances between exteroceptive/interoceptive inputs across brain and whole-body levels (cardiometabolic, cardiovascular, inflammatory, immune). This approach offers new insights, presenting novel perspectives on brain spatiotemporal hierarchies and interactions. By integrating these theories, the paper opens innovativ

Who reads Intrinsic Timescales and Predictive Allostatic Interoception in Brain Health and Disease?

It is typically read by researchers, students, and practitioners in Neuroscience.

Author
Agustin Ibanez; Georg Northoff
Publisher
Elsevier BV
Published
2024
Language
EN
Field
Neuroscience (Life Sciences)

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