Can I read Molecular genetics of aging in the fly: Is this the end of the beginning? on EtoBox?

Molecular genetics of aging in the fly: Is this the end of the beginning? by Stephen L. Helfand; Blanka Rogina is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Molecular genetics of aging in the fly: Is this the end of the beginning? about?

## Abstract How we age and what we can do about it have been uppermost in human thought since antiquity. The many false starts have frustrated experimentalists and theoretical arguments pronouncing the inevitability of the process have created a nihilistic climate among scientists and the public. The identification of single gene alterations that substantially extend life span in nematodes and flies however, have begun to reinvigorate the field. __Drosophila__'s long history of contributions to aging research, rich storehouse of genetic information, and powerful molecular techniques make it an excellent system for studying the molecular mechanisms underlying the process of aging. In recent years, __Drosophila__ has been used to test current theories on aging and explore new directions of potential importance to the biology of aging. One such example is the surprising finding that, as opposed to the commonly held assumption that adult life is a period of random passive decline in which all things are thought to fall apart, the molecular life of the adult fly appears to be a state of dynamic well‐regulated change. In the fly, the level of expression of many different genes changes in

Who reads Molecular genetics of aging in the fly: Is this the end of the beginning??

Author

Stephen L. Helfand; Blanka Rogina

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0265-9247)

Published

2003

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)