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Nutritional, phytochemical, and in vitro anticancer potential of sugar apple (Annona squamosa) fruits by Shehata, Mohamed Gamal (author);Abu-Serie, Marwa Muhammad (author);Abd El-Aziz, Nourhan Mohammad (author);El-Sohaimy, Sobhy Ahmed (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Nutritional, phytochemical, and in vitro anticancer potential of sugar apple (Annona squamosa) fruits about?
In plants, Fruits and their wastes are the main sources of bioactive compounds. Currently, Annona fruits have attracted the attention of people interested in health-promoting foods due to their phytochemical content that their activities were not studied before. This study aimed to explore the potential antioxidant, antimicrobial, and in vitro anticancer activity of two cultivars Annona squamosa (Annona b. and Annona h.) seed, peel, and pulp. We also meausred phenolic, flavonoid, sulfated polysaccharide, tannins, and triterpenoids. Polyphenol identification was determined using RP-HPLC. Results of the antioxidant activity revealed that the highest activity was observed for Annona h. seed extract using DPPH and ABTS assays with IC 50 6.07 ± 0.50 and 9.58 ± 0.53 μg/ml, respectively. ## The antimicrobial activity against various pathogenic strains revealed that the peel extracts of both Annona b. and Annona h. exhibited the best antimicrobial activity. We also assessed the IC 50 values for anticancer activity in all six Annona b. and Annona h samples against four cancer cell lines colon (Caco-2), prostate (PC3), liver (HepG-2), and breast (MCF-7) using MTT assay. Annona b. and Annona
Who reads Nutritional, phytochemical, and in vitro anticancer potential of sugar apple (Annona squamosa) fruits?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Shehata, Mohamed Gamal (author);Abu-Serie, Marwa Muhammad (author);Abd El-Aziz, Nourhan Mohammad (author);El-Sohaimy, Sobhy Ahmed (author)
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)