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This review discusses the use of glucocorticoids (GCs) in treating Systemic Lupus Erythematosus (SLE), highlighting their anti-inflammatory effects and the associated risks of long-term high-dose therapy. It proposes a new treatment paradigm that emphasizes the use of methylprednisolone pulses followed by lower doses of prednisone to minimize adverse effects while maintaining efficacy. The review aims to address common clinical questions and optimize GC dosing strategies based on current evidence.

Author

Erick B. Pordeus

Language

EN