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Economic burden and health-related quality-of-life among infants with respiratory syncytial virus infection: A multi-country prospective cohort study in Europe by Zhuxin Mao; Xiao Li; Ana Dacosta-Urbieta; Marie-Noëlle Billard; Joanne Wildenbeest; Koos Korsten; Federico Martinón-Torres; Terho Heikkinen; Steve Cunningham; Matthew D. Snape; Hannah Robinson; Andrew J. Pollard; Maarten Postma; Benoit Dervaux; Niel Hens; Louis Bont; Joke Bilcke; Philippe Beutels is a Medicine article available to read on EtoBox.

What is Economic burden and health-related quality-of-life among infants with respiratory syncytial virus infection: A multi-country prospective cohort study in Europe about?

Background Respiratory syncytial virus (RSV) causes a considerable disease burden in young children globally, but reliable estimates of RSV-related costs and health-related quality-of-life (HRQoL) are scarce. This study aimed to evaluate the RSV-associated costs and HRQoL effects in infants and their caregivers in four European countries. Methods Healthy term-born infants were recruited at birth and actively followed up in four European countries. Symptomatic infants were systematically tested for RSV. Caregivers recorded the daily HRQoL of their child and themselves, measured by a modified EQ-5D with Visual Analogue Scale, for 14 consecutive days or until symptoms resolved. At the end of each RSV episode, caregivers reported healthcare resource use and work absenteeism. Direct medical costs per RSV episode were estimated from a healthcare payer’s perspective and indirect costs were estimated from a societal perspective. Means and 95% confidence intervals (CI) of direct medical costs, total costs (direct costs + productivity loss) and quality-adjusted life-day (QALD) loss per RSV episode were estimated per RSV episode, as well as per subgroup (medical attendance, country). Results

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Author

Zhuxin Mao; Xiao Li; Ana Dacosta-Urbieta; Marie-Noëlle Billard; Joanne Wildenbeest; Koos Korsten; Federico Martinón-Torres; Terho Heikkinen; Steve Cunningham; Matthew D. Snape; Hannah Robinson; Andrew J. Pollard; Maarten Postma; Benoit Dervaux; Niel Hens; Louis Bont; Joke Bilcke; Philippe Beutels

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)