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Treatment-related thoracic soft tissue sarcomas in US breast cancer survivors: a retrospective cohort study by Lene H S Veiga; Jacqueline B Vo; Rochelle E Curtis; Matthew M Mille; Choonsik Lee; Cody Ramin; Clara Bodelon; Erin J Aiello Bowles; Diana S M Buist; Sheila Weinmann; Heather Spencer Feigelson; Gretchen L Gierach; Amy Berrington de Gonzalez is a Medicine article available to read on EtoBox.
What is Treatment-related thoracic soft tissue sarcomas in US breast cancer survivors: a retrospective cohort study about?
## Background: Soft tissue sarcoma is a rare but serious side-effect of radiotherapy to treat breast cancer, and rates are increasing in the usa. we evaluated potential co-factors in two complimentary cohorts of us breast cancer survivors. ## Methods: In this retrospective cohort study, we sourced data from the kaiser permanente (kp) cohort and the surveillance, epidemiology, and end results (seer) 13 registries cohort, both in the usa. the kp cohort included 15 940 women diagnosed with breast cancer from jan 1, 1990, to dec 31, 2016, in kp colorado, kp northwest (which serves oregon and southwest washington state), or kp washington, with detailed treatment data and comorbidities (including hypertension and diabetes at or before breast cancer diagnosis) from electronic medical records. the seer cohort included 457 300 women diagnosed with breast cancer from jan 1, 1992, to dec 31, 2016, within the 13 seer registries across the usa, with initial treatment data (yes vs no or unknown). eligibility criteria in both cohorts were female breast cancer survivors (stage i-iii) aged 20-84 years at diagnosis who had breast cancer surgery, and had survived at least 1 year after breast cancer d
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- Author
- Lene H S Veiga; Jacqueline B Vo; Rochelle E Curtis; Matthew M Mille; Choonsik Lee; Cody Ramin; Clara Bodelon; Erin J Aiello Bowles; Diana S M Buist; Sheila Weinmann; Heather Spencer Feigelson; Gretchen L Gierach; Amy Berrington de Gonzalez
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)