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Early vs. Delayed Mechanical Circulatory Support in Patients with Acute Myocardial Infarction and Cardiogenic Shock by Kevin G Buda; Katarzyna Hryniewicz; Peter M Eckman; Mir B Basir; Jennifer A Cowger; Khaldoon Alaswad; Srini Mukundan; Yader Sandoval; Andrea Elliott; Emmanouil S Brilakis; Michael S Megaly is a Medicine article available to read on EtoBox.

What is Early vs. Delayed Mechanical Circulatory Support in Patients with Acute Myocardial Infarction and Cardiogenic Shock about?

## Abstract ## Background Despite increased temporary mechanical circulatory support (tMCS) utilization for acute myocardial infarction complicated by cardiogenic shock (AMI-CS), data regarding efficacy and optimal timing for tMCS support are limited. This study aimed to describe outcomes based on tMCS timing in AMI-CS and to identify predictors of 30-day mortality and readmission. ## Methods Patients with AMI-CS identified in the National Readmissions Database were grouped according to the use of tMCS and early (<24 hours) vs. delayed (≥24 hours) tMCS. The correlation between tMCS timing and inpatient outcomes was evaluated using linear regression. Multivariate logistic regression was used to identify variables associated with 30-day mortality and readmission. ## Results Of 294,839 patients with AMI-CS, 109,148 patients were supported with tMCS (8,067 veno-arterial extracorporeal membrane oxygenation, 33,577 Impella, and 79,161 intra-aortic balloon pump). Of patients requiring tMCS, patients who received early tMCS (n = 79,906) had shorter lengths of stay (7 days vs. 15 days, p < 0.001) and lower rates of ischemic and bleeding complications than those with delayed tMCS (n = 32,241

Who reads Early vs. Delayed Mechanical Circulatory Support in Patients with Acute Myocardial Infarction and Cardiogenic Shock?

Author

Kevin G Buda; Katarzyna Hryniewicz; Peter M Eckman; Mir B Basir; Jennifer A Cowger; Khaldoon Alaswad; Srini Mukundan; Yader Sandoval; Andrea Elliott; Emmanouil S Brilakis; Michael S Megaly

Publisher

Oxford University Press (OUP)

Published

2024

Language

EN

Field

Medicine (Health Sciences)