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This study investigates the antiemetic effects of nerolidol (NDL) in combination with other drugs using in vivo and in silico methods. Results show that NDL significantly reduces the number of retches and delays emetic onset in chicks, with enhanced efficacy when combined with domperidone, hyoscine, and ondansetron. The findings suggest that NDL has potential as a natural antiemetic agent, particularly through its interactions with muscarinic receptors.
- Author
- iimeliaeka
- Language
- EN