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Large Granular Lymphocyte Leukemia with Pure Red Cell Aplasia in a Renal Transplant Recipient by Masuda, Michihiko; Arai, Yukari; Nishina, Hiroyuki; Fuchinoue, Shouhei; Mizoguchi, Hideaki is a Medicine article available to read on EtoBox.
What is Large Granular Lymphocyte Leukemia with Pure Red Cell Aplasia in a Renal Transplant Recipient about?
Neoplastic disorders sometimes accompany a renal transplant. Herein, we report a large granular lymphocyte (LGL) leukemia patient with pure red cell aplasia (PRCA) after renal transplantation. A 36-year-old female was presented to our department with anemia in February 1996. She had undergone hemodialysis because of pregnancy in December 1981. She received a renal transplantation from her mother in April 1986. After the transplantation, she received cyclosporin A (CyA) at 2 mg/kg/day, mizoribine at 1 mg/kg/day, and methylprednisolone at 0.1 mg/kg/day for 8 years. In July 1995, her hemoglobin level dropped to 9.3 g/dl, and anemia developed gradually. In January 1996, her hemoglobin was 5.8 g/dl, and she was given a red blood cell transfusion. Laboratory findings were as follows: RBC 1.46 x 10(12)/L; hemoglobin 5.8 g/dl; hematocrit 17.8%; leucocytes 5.2 x 10(9)/L with 62.4% neutrophils, 34.1% lymphocytes, 2.6% monocytes; platelets 50.8 x 10(10)/L; reticulocytes 0.4%. Bone marrow aspirate smears and biopsy sections revealed normal myeloid and megakaryocyte differentiation with few erythroid precursors. The lymphocytes were of medium size with granules in the cytoplasm. More than 90% o
Who reads Large Granular Lymphocyte Leukemia with Pure Red Cell Aplasia in a Renal Transplant Recipient?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Masuda, Michihiko; Arai, Yukari; Nishina, Hiroyuki; Fuchinoue, Shouhei; Mizoguchi, Hideaki
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0361-8609)
- Published
- 1998
- Language
- EN
- Field
- Medicine (Health Sciences)