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What is In Situ Gel for Ocular Drug Delivery about?

This study focuses on developing a thermoresponsive ophthalmic in situ gel containing Dexamethasone sodium phosphate and Tobramycin sulphate using a Quality by Design (QbD) approach to enhance ocular bioavailability and prolong pre-corneal residence time. The formulation was optimized through central composite design, resulting in improved drug release and corneal penetration compared to existing products. The findings suggest that the developed gel could effectively treat ocular inflammation and infections

Author

shrutinarkhede24

Language

EN