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Can I read Prostatic radioimmunoscintigraphy: preliminary results using technetium-labelled monoclonal antibody, CYT-351 on EtoBox?
Prostatic radioimmunoscintigraphy: preliminary results using technetium-labelled monoclonal antibody, CYT-351 by M.R. Feneley; V.U. Chengazi; R.S. Kirby; C.C. Nimmon; M. Granowska; S.J. Mather; D. Ellison; A.R. Granowski; K.E. Britton is a Medicine article available to read on EtoBox.
What is Prostatic radioimmunoscintigraphy: preliminary results using technetium-labelled monoclonal antibody, CYT-351 about?
## Objective: To investigate the clinical application of a new technique for imaging prostatic malignancy using planar imaging and single-photon emission tomography (spet) with technetium-99m-labelled antibody to a prostatic cell surface membrane antigen. ## Patients and methods: Prostatic malignancy was imaged by radioimmunoscintigraphy (ris) using a 99mtc-labelled monoclonal antibody, cyt-351, raised against a newly identified membrane antigen present in normal and malignant prostatic tissues. the protocol involved taking serial images and assessing the changes in activity, as the uptake of specific antibody increased with time and non-specific uptake decreased. data from planar images were collected at 10 min, 6 and 24 h after injection with antibody, and by spet at 6 and 24 h using a siemens orbiter large field of view gamma camera. twenty-two ris scans were evaluated, which included six patients with clinically localized disease, six patients with previous incidental carcinoma at prostatectomy for apparently benign disease, four patients with evidence of local recurrence after radical prostatectomy and six patients with metastatic disease. ## Results: Primary tumours and secon
Who reads Prostatic radioimmunoscintigraphy: preliminary results using technetium-labelled monoclonal antibody, CYT-351?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- M.R. Feneley; V.U. Chengazi; R.S. Kirby; C.C. Nimmon; M. Granowska; S.J. Mather; D. Ellison; A.R. Granowski; K.E. Britton
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1464-4096)
- Published
- 1996
- Language
- EN
- Field
- Medicine (Health Sciences)