About this document
Modified Michaelis-Menten in Pharmacokinetics by ירדן לוין is a document available to read on EtoBox.
The document discusses the application of modified Michaelis-Menten equations to determine enzyme inducing and inhibiting drugs. It provides 19 equations to translate in vitro enzyme kinetics to pharmacokinetic parameters. Some key points include: 1) The Michaelis-Menten equation and its derivatives can be used to calculate parameters like maximum metabolic rate, metabolic constant, and factors influencing drug metabolism. 2) Drugs like theophylline and voriconazole are enzyme inducers while mibefradil a
- Author
- ירדן לוין
- Language
- EN