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What is Enhancing Tadalafil Dissolution via Solid Dispersion about?

This document discusses a study that aimed to improve the dissolution and bioavailability of the poorly water-soluble drug Tadalafil using solid dispersion techniques. Tadalafil solid dispersions were prepared using PVP K30 and PEG 6000 as carriers by melting, solvent evaporation, and co-grinding methods. The dispersions were characterized using FTIR, DSC, XRD, and SEM analysis and showed improved dissolution compared to pure Tadalafil powder in vitro. The results indicate that solid dispersion techniques c

Author

dini hanifa

Language

EN