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Gap Junctions and Tumor Growth Control by Kash Evangelina is a document available to read on EtoBox.
1. The study compared the growth rates of parental human tumor cells (SKHepl) with clones stably transfected with cDNA encoding the gap junction protein connexin 32. 2. In culture, the growth rates of parental and transfected cells were similar. However, when injected into nude mice, tumors formed from well-coupled transfected clones grew significantly slower than tumors from poorly coupled clones or parental cells. 3. The results support the hypothesis that strong coupling between malignant cells via ga
- Author
- Kash Evangelina
- Language
- EN