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Can I read Passerini-type Reaction of Boronic Acids Enables α-Hydroxyketones Synthesis on EtoBox?
Passerini-type Reaction of Boronic Acids Enables α-Hydroxyketones Synthesis by Yang, Kai (author);Zhang, Feng (author);Fang, Tongchang (author);Li, Chaokun (author);Li, Wangyang (author);Song, Qiuling (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Passerini-type Reaction of Boronic Acids Enables α-Hydroxyketones Synthesis about?
## Abstract Multicomponent reactions (MCRs) facilitate the rapid and diverse construction of molecular scaffolds with modularity and step economy. In this work, engagement of boronic acids as carbon nucleophiles culminates in a Passerini-type three-component coupling reaction towards the synthesis of an expanded inventory of α-hydroxyketones with skeletal diversity. In addition to the appealing features of MCRs, this protocol portrays good functional group tolerance, broad substrate scope under mild conditions and operational simplicity. The utility of this chemistry is further demonstrated by amenable modifications of bioactive products and pharmaceuticals as well as in the functionalization of products to useful compounds.
Who reads Passerini-type Reaction of Boronic Acids Enables α-Hydroxyketones Synthesis?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Yang, Kai (author);Zhang, Feng (author);Fang, Tongchang (author);Li, Chaokun (author);Li, Wangyang (author);Song, Qiuling (author)
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)