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Preparation, Characterization and in Vitro Biocompatibility Evaluation of Poly(butylene Terephthalate)/wollastonite Composites by Makarand Risbud; D Nabi Saheb; Jyoti Jog; Ramesh Bhonde is a Engineering article available to read on EtoBox.

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The aim of the study was to prepare composites of poly(butylene terepthalate)/wollastonite (PBT/W), evaluate their properties and in vitro biocompatibility. Composites of PBT with wollastonite in two di!erent proportions, viz. 70/30 (PW-30), 50/50 (PW-50) were prepared. The DSC studies indicate marginal changes in the melting behavior and enhanced crystallization in PBT/W composites. The mechanical properties of the composites such as tensile modulus shows remarkable improvement as a result of incorporation of wollastonite. SEM studies of fractured surfaces of impact samples showed no evidence of bonding between PBT and wollastonite. Water contact angle of PW30 and PW50 was 73.7 and 78.73, respectively. In vitro biocompatibility of PW-30 was evaluated as a representative composite. Direct cell contact test did not show deleterious e!ects on NIH3T3 "broblast morphology and DNA integrity indicating its compatibility. Leach out products (LOP) of PW-30 were evaluated non-toxic as tested by MTT assay. Mouse peritoneal macrophages in contact with PW-30 showed comparable expression of CD 11b/18, CD45, CD14 and B7.2 to macrophages in contact with PTFE control indicating its non-activating

Who reads Preparation, Characterization and in Vitro Biocompatibility Evaluation of Poly(butylene Terephthalate)/wollastonite Composites?

Author

Makarand Risbud; D Nabi Saheb; Jyoti Jog; Ramesh Bhonde

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0142-9612)

Published

2001

Language

EN

Field

Engineering (Physical Sciences)