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Evaluation of Levels of Interleukin-6, Interleukin-8 and Some Haematologic Parameters of Dogs with Cutaneous Wounds by Avazi, Daniel Onimisi; Awasum, Augustine Cheh; Hassan, Adamu Zoaka; Ayo, Joseph Olusegun; Aluwong, Tagang; Muhammed, Sa'idu Tanko; Simon, Ayo Yila; Suleiman, Mohammad Hadi; Kudi, Ayuba Caleb is a Immunology and Microbiology article available to read on EtoBox.
What is Evaluation of Levels of Interleukin-6, Interleukin-8 and Some Haematologic Parameters of Dogs with Cutaneous Wounds about?
The aim of the study was to investigate the time-course of serum and wound fluids interleukin (IL)-6 and IL-8 levels in dogs with cutaneous wounds and their relationship with some haematologic parameters. The experimental group comprised of six adult dogs that underwent surgery with wounds (n = 6) on the mid lateral aspect of the right antebrachium; and control group of six, apparently, healthy intact (free from cutaneous wounds) adult dogs, comprising equal number of both sexes. Vital signs evaluated were within normal limits. Samples of blood, serum and wound fluids harvested pre- and at 12 h, 36 h, 60 h, 156 h and 324 h post-injury, were utilised for IL-6 and IL-8 assay and haematology. Peak concentrations of IL-6 in wound fluid (1.33. ± 0.33 ng/mL) and serum (0.82 ± 0.24 ng/mL) of the experimental group at 12 h post-operation were higher (P < 0.01) than the control (0.30 ± 0.05 ng/mL). Concentrations of IL-8 at 12 h and 60 h in wound fluid (0.21 ± 0.05 ng/mL and 0.22 ± 0.11 ng/mL) respectively were lower (P < 0.05) than serum (0.71 ± 0.21 ng/mL and 0.73 ± 0.24 ng/mL) respectively in the experimental group and corresponding values recorded in controls (0.34 ± 0.09 ng/mL and 0.36
Who reads Evaluation of Levels of Interleukin-6, Interleukin-8 and Some Haematologic Parameters of Dogs with Cutaneous Wounds?
It is typically read by researchers, students, and practitioners in Immunology and Microbiology.
- Author
- Avazi, Daniel Onimisi; Awasum, Augustine Cheh; Hassan, Adamu Zoaka; Ayo, Joseph Olusegun; Aluwong, Tagang; Muhammed, Sa'idu Tanko; Simon, Ayo Yila; Suleiman, Mohammad Hadi; Kudi, Ayuba Caleb
- Publisher
- Elsevier Science; Elsevier ; Elsevier Inc.; Elsevier BV (ISSN 1043-4666)
- Published
- 2018
- Language
- EN
- Field
- Immunology and Microbiology (Life Sciences)