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Impact of gestational hypertension and pre-eclampsia on preterm birth in China: a large prospective cohort study by Hang An; Ming Jin; Zhiwen Li; Le Zhang; Hongtian Li; Yali Zhang; Rongwei Ye; Nan Li is a Medicine article available to read on EtoBox.

What is Impact of gestational hypertension and pre-eclampsia on preterm birth in China: a large prospective cohort study about?

## Objective To investigate the impact of gestational hypertension and pre-eclampsia on preterm birth. ## Design The data were collected from the China–US Collaborative Project for Neural Tube Defect Prevention; this was a large population-based cohort study. ## Setting and participants We selected participants registered in two southern provinces, for whom we had exact information on gestational blood pressure and pregnancy outcomes, and who were not affected by chronic hypertension. In total, 200 103 participants were recruited from 1993 to 1995. ## Outcome measures Preterm birth was defined as a singleton pregnancy and birth before 37 gestational weeks. ## Results The incidences of gestational hypertension and pre-eclampsia were 5.47% and 5.44%, respectively, for women who gave birth at full term, and 5.63% and 7.33%, respectively, for those who gave birth preterm. After adjusting for potential confounders, the risk ratios (RRs) of preterm birth in women with gestational hypertension and pre-eclampsia were 1.04 (95% CI 0.98 to 1.11) and 1.39 (95% CI 1.25 to 1.55), respectively. The associations were stronger for early-onset (<28 weeks of gestation) gestational hypertension (adju

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Author
Hang An; Ming Jin; Zhiwen Li; Le Zhang; Hongtian Li; Yali Zhang; Rongwei Ye; Nan Li
Published
2022
Language
EN
Field
Medicine (Health Sciences)

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