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Can I read Ligand-induced melting reaction of specific-sequence DNA molecules on EtoBox?
Ligand-induced melting reaction of specific-sequence DNA molecules by Hideki Tachibana; Akiyoshi Wada is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Ligand-induced melting reaction of specific-sequence DNA molecules about?
## Abstract An algorithm for the calculation of ligand‐induced helix–coil transitions of macromolecules of any specific sequence was derived. The probabilities of each residue to be in helix and ligand‐free, helix and ligand‐bound, coil and ligand‐free, and coil and ligand‐bound states can be calculated by extending the recursion relation formula proposed by D. Poland [(1974) __Biopolymers__ **13**, 1859–1871]. Calculations using hypothetical DNAs having block heterogeneities for melting reactions showed that cooperative binding specific to single strands weakens the effect of the heterogeneity. Fine structures in the melting profiles or cooperatively melting regions, which have so far been found in thermal melting experiments, were predicted to exist in ligand‐induced melting reactions for natural DNA fragments.
Who reads Ligand-induced melting reaction of specific-sequence DNA molecules?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Hideki Tachibana; Akiyoshi Wada
- Publisher
- Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0006-3525)
- Published
- 1982
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)