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Food Antibodies in Patients with Dermatitis Herpetiformis and Adult Coeliac Disease – Relationship to Jejunal Morphology by Kumar, Parveen J.; Ferguson, Anne; Lancaster-Smith, M.; Clark, M. L. is a Medicine article available to read on EtoBox.

What is Food Antibodies in Patients with Dermatitis Herpetiformis and Adult Coeliac Disease – Relationship to Jejunal Morphology about?

Serum antibodies to a variety of dietary proteins were investigated in 26 patients with adult coeliac disease (ACD, 14 untreated and 17 treated with a gluten-free diet) and 38 patients with dermatitis herpetiformis (DH) with varying small bowel abnormalities. The incidence of one or more positive tests was highest in untreated ACD (73.4%) and DH with subtotal villous atrophy (57.4%). This incidence fell with morphological improvement, being 56.4% in treated ACD patients with partial villous atrophy (PVA), and 33.4% in DH with PVA, and 0% in DH with normal biopsies. The height of the serum antibody titre also fell with morphological improvement. These results show that there is an abnormally high incidence of dietary antibodies in patients with DH, and this correlates with the degree of small bowel damage.

Who reads Food Antibodies in Patients with Dermatitis Herpetiformis and Adult Coeliac Disease – Relationship to Jejunal Morphology?

Author

Kumar, Parveen J.; Ferguson, Anne; Lancaster-Smith, M.; Clark, M. L.

Publisher

Informa plc; Informa UK (Taylor & Francis); Taylor & Francis; Informa UK Limited (ISSN 0036-5521)

Published

1976

Language

EN

Field

Medicine (Health Sciences)