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This systematic review and network meta-analysis evaluated the efficacy of adjunctive antidepressants, specifically mirtazapine and duloxetine, in treating negative symptoms of schizophrenia. The analysis included 15 studies with 655 patients and found that both mirtazapine and duloxetine significantly improved negative symptoms compared to placebo. The findings suggest that incorporating these antidepressants into treatment plans for schizophrenia may be beneficial and warrant further investigation.

Author

Samirpsyche7

Language

EN