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Can I read Mapping Neutralizing and Non-Neutralizing Epitopes on the Capsid Protein of Feline Calicivirus on EtoBox?

Mapping Neutralizing and Non-Neutralizing Epitopes on the Capsid Protein of Feline Calicivirus by K. GEISSLER; K. SCHNEIDER; U. TRUYEN is a Agricultural and Biological Sciences article available to read on EtoBox.

What is Mapping Neutralizing and Non-Neutralizing Epitopes on the Capsid Protein of Feline Calicivirus about?

Neutralizing epitopes on feline calicivirus (FCV) capsid protein were mapped using chimeric capsid proteins recombinant between two FCV isolates that do not show any cross‐neutralization. The three chimeric proteins examined were expressed in murine L929 cells employing an MVA/T7 vaccinia virus expression system and inoculated into major histocompatibility complex haplotype‐matched C3/HN mice. Based on the neutralizing antibody titre the neutralizing epitope(s) could be mapped to the 5′ hypervariable region of the E region or potentially to the C region. The epitopes of some non‐neutralizing antibodies were mapped with the same chimeric proteins to the regions B or D and F of the FCV capsid protein.

Who reads Mapping Neutralizing and Non-Neutralizing Epitopes on the Capsid Protein of Feline Calicivirus?

It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.

Author
K. GEISSLER; K. SCHNEIDER; U. TRUYEN
Publisher
John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0931-1793)
Published
2002
Language
EN
Field
Agricultural and Biological Sciences (Life Sciences)

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