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Radioactivity-Guided Isolation and Characterization of the Bicyclic Pseudopterosin Diterpene Cyclase Product from Pseudopterogorgia elisabethae by Amber C. Coleman; Russell G. Kerr is a Chemistry article available to read on EtoBox.

What is Radioactivity-Guided Isolation and Characterization of the Bicyclic Pseudopterosin Diterpene Cyclase Product from Pseudopterogorgia elisabethae about?

AbstractÐThe intermediate representing the ®rst committed step in the pseudopterosin biosynthetic pathway has been discovered using a radioactivity-guided isolation. This diterpene cyclase product was identi®ed from a cell-free extract of the marine soft coral, Pseudopterogorgia elisabethae, which was incubated with 3 H-geranylgeranyl diphosphate. Structural studies of the compound have revealed an unexpected bicyclic skeleton suggesting that the pseudopterosins are related to the seco-pseudopterosins through a common bicyclic intermediate. In addition, the intermediacy of this metabolite in pseudopterosin biosynthesis has been con®rmed utilizing a cell-free extract of P. elisabethae.

Who reads Radioactivity-Guided Isolation and Characterization of the Bicyclic Pseudopterosin Diterpene Cyclase Product from Pseudopterogorgia elisabethae?

It is typically read by researchers, students, and practitioners in Chemistry.

Author
Amber C. Coleman; Russell G. Kerr
Publisher
Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4020)
Published
2000
Language
EN
Field
Chemistry (Physical Sciences)

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