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Antifungal drugs are designed to treat fungal infections by selectively targeting structures unique to fungi, such as ergosterol and cell wall components, while minimizing harm to human cells. Major classes of antifungal agents include polyenes, allylamines, azoles, echinocandins, and antimetabolites, each with distinct mechanisms of action and clinical uses. Fungal drug resistance is a growing concern, often arising from mutations, efflux pumps, and biofilm formation.
- Author
- chidubemnnabueze
- Language
- EN