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Protonation, conformation and hydrogen bonding of nicotinamide adenine dinucleotide — an FT-IR study by Carsten Nadolny; Georg Zundel is a Chemistry article available to read on EtoBox.

What is Protonation, conformation and hydrogen bonding of nicotinamide adenine dinucleotide — an FT-IR study about?

Earlier RAMAN studies have shown that a strong interaction of NAD + with alcohol dehydrogenases occurs. In this paper nicotinamide adenine dinucleotide (NAD ÷) is studied by FF-IR difference spectroscopy. The pH dependence of NAD + is investigated, as well as the influence of conformational changes and hydrogen bonding on the spectra. With the protonation of NAD ÷ four bands disappear. These bands are characteristic for the protonation of the N a atom of the adenine residue. They are not influenced by a change from a closed to an expanded conformation of NAD ÷. The formation of hydrogen bonds shifts these bands only slightly toward higher wavenumbers. These results are the basis of a better understanding of the NAD+-alcohol dehydrogenase interaction.

Who reads Protonation, conformation and hydrogen bonding of nicotinamide adenine dinucleotide — an FT-IR study?

It is typically read by researchers, students, and practitioners in Chemistry.

Author
Carsten Nadolny; Georg Zundel
Publisher
Elsevier Science; Elsevier ; Elsevier BV (ISSN 0022-2860)
Published
1996
Language
EN
Field
Chemistry (Physical Sciences)

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