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Aptamer-AuNP SPR Sensor for Small Molecules by Muslimahdzakiyah is a document available to read on EtoBox.
This document describes a new surface plasmon resonance (SPR) method for detecting small molecules using aptamers and gold nanoparticles. Small molecules are difficult to detect using conventional SPR due to the small refractive index changes upon binding. The new method addresses this by using aptamers immobilized on the SPR sensor surface that can selectively bind small molecules and undergo a conformational change. Gold nanoparticles tagged with complementary DNA strands are then used to amplify the SPR
- Author
- Muslimahdzakiyah
- Language
- EN