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Potential Elimination of Human Gut Resistome by Exploiting the Benefits of Functional Foods by Tsigalou, Christina; Konstantinidis, Theocharis; Stavropoulou, Elisavet; Bezirtzoglou, Eugenia E.; Tsakris, Athanasios is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Potential Elimination of Human Gut Resistome by Exploiting the Benefits of Functional Foods about?

Recent advances in technology over the last decades have strived to elucidate the diverse and abundant ecosystem of the human microbiome. The intestinal microbiota represents a densely inhabited environment that offers a plethora of beneficial effects to the host’s wellbeing. On the other hand, it can serve as a potential reservoir of Multi-Drug Resistant (MDR) bacteria and their antibiotic-resistant genes (ARgenes), which comprise the “gut resistome.” ARgenes, like antibiotics, have been omnipresent in the environment for billions of years. In the context of the gut microbiome, these genes may conflate into exogenous MDR or emerge in commensals due to mutations or gene transfers. It is currently generally accepted that Antimicrobial Resistance (AMR) poses a serious threat to public health worldwide. It is of paramount importance that researchers focus on, amongst other parameters, elaborating strategies to manage the gut resistome, particularly focusing on the diminution of AMR. Potential interventions in the gut microbiome field by Fecal Microbiota Transplant (FMT) or functional foods are newly emerged candidates for the uprooting of MDR strains and restoring dysbiosis and resili

Who reads Potential Elimination of Human Gut Resistome by Exploiting the Benefits of Functional Foods?

Author

Tsigalou, Christina; Konstantinidis, Theocharis; Stavropoulou, Elisavet; Bezirtzoglou, Eugenia E.; Tsakris, Athanasios

Publisher

Frontiers; Frontiers Media SA; Frontiers Media S.A.; Lausanne: Frontiers Media S.A., 2010-; Publons (ISSN 1664-302X)

Published

2020

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)