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JSR and EJSR in the Finch Heart: Morphometry by Serial Sections. by J.R. Sommer; T. High; R. Nassar; I. Taylor is a Materials Science article available to read on EtoBox.

What is JSR and EJSR in the Finch Heart: Morphometry by Serial Sections. about?

“Coupling(s)” (Fig. 1) are structure complexes in cardiac muscle consisting of junctional SR (JSR) tightly apposed to the cytoplasmic side of the plasmalemma. They are either peripheral (PC; when on the cell surface) or interior (IC; when on transverse tubule(s), TT). The JSR is a store for calcium (Ca)-release through Ca channels/ryanodine receptors in junctional processe(s) (JP) on the JSR surfaces. Action potential(s) (AP) for excitation-contraction coupling translate, as mediated by L-type channels, into Ca-entry into a ̃ 20 nm junctional gap (JG) containing JP between plasmalemma and the JSR's junctional membrane proper. In mammalian cardiac myocyte(s) (CM), where IC are ubiquitously distributed along TT at Z-bands, an AP quickly effects almost simultaneous global contraction, even in the center of cells of large diameter, whence CICR can be viewed as a one-step event between Ca-entry and JSR Ca-release from couplings. Avian CM, however, have no TT and, thus, only PC.

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Author

J.R. Sommer; T. High; R. Nassar; I. Taylor

Publisher

Oxford University Press (OUP)

Published

1997

Language

EN

Field

Materials Science (Physical Sciences)