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Defined Synthetic Vaccines by Wolfgang Zauner; Karen Lingnau; Frank Mattner; Alexander von Gabain; Michael Buschle is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Defined Synthetic Vaccines about?

## Defined Synthetic Vaccines pounds. These formulations should be safer, more efficient, easier and cheaper to produce. This review focuses on recent developments in synthetic vaccines. It is an attempt at summarizing the data available on synthetic antigens as well as known synthetic adjuvants (including possible modes of action) and focuses on a potential new class of adjuvants, namely polycationic peptides. Different approaches toward better-defined vaccines, such as subunit vaccines, which use purified or recombinant proteins derived from pathogens, and DNA vaccines have been reviewed recently and are not the topic of this review article (Ben-Yedida and Arnon, 1997;Donnelly et al., 1997). Well-defined, but non-synthetic adjuvants, such as conjugates of cholera toxin (from Vibrio cholerae) and heat labile enterotoxin (from Escherichia coli), interleukins, immune stimulatory complexes (ISCOM) and compounds purified from natural sources (saponins, QS 21, monophosphoryl lipid A), will not be covered either. The reader is referred to other reviews dealing with these topics (Heath and Playfair, 1992;

Who reads Defined Synthetic Vaccines?

Author

Wolfgang Zauner; Karen Lingnau; Frank Mattner; Alexander von Gabain; Michael Buschle

Publisher

Walter de Gruyter GmbH

Published

2001

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)